In the pharmaceutical industry, reaction kettles are common process equipment, and they can appear in various forms according to different uses, such as crystallization kettles, synthesis kettles, hydrogenation kettles, etc. In the research and development, preparation or synthesis reaction process of pharmaceutical and chemical industry, the accurate control of the temperature in the kettle is the key factor to determine the reaction, and the temperature control curve parameter of the cooling & heating system is one of the main controlled quantities in the reaction process.
In the chemical reaction process, the reactor is one of the links in the production process, and the design of the reactor and the selection of supporting facilities are often very important. Compared with other monomer process equipment, the reactor mainly completes the mass transfer and heat transfer of the reaction system, and the effective transfer and accurate control of energy (cold/heat) will directly affect the temperature control accuracy of the reactor.
According to the characteristics of the reaction, the reactor can be divided into endothermic reaction and exothermic reaction. In general, polymerization reactions are exothermic reactions, while fission reactions are endothermic reactions. The operation process of the reactor generally includes four stages of preheating, heating, constant temperature and cooling. Among them, the constant temperature section is a key stage reflecting the process, which has an impact on product quality and output, so improving the control accuracy of the constant temperature section of the cooling & heating system is the key to improving product quality.
The actual reaction process of cooling & heating system is often accompanied by a strong exothermic effect, which changes the reaction temperature. According to the characteristics of the temperature control of the reactor, the equipment adopts the reactor cooling & heating system based on PID control, and through the online learning function of the neural network, the automatic adjustment and self-adaptive ability of the system are enhanced to make the reactor control more stable.
A chemical reactor is usually a complex system involving various factors such as temperature, pressure, concentration, flow, etc. The quality of the production process largely depends on the control of process parameters (such as temperature, pressure, flow, etc.). Therefore, the temperature, pressure, flow rate and composition of materials in the cooling & heating system are stable during the production process, which can greatly improve the quality and output of the product, and achieve the goals of stability, reliability, production, energy saving and consumption reduction, thereby improving production efficiency , increase the economic benefits of the enterprise.
The temperature control accuracy of the reaction process is being paid attention to by more and more pharmaceutical companies. With the emergence of specific process energy control and accurate control units, the cooling & heating system can continuously realize the innovation of original research drugs, continuously improve the quality of generic drugs, and reduce the overall operating costs for enterprises. Provide strong protection.
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